Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGM5 All Species: 27.27
Human Site: S525 Identified Species: 40
UniProt: Q15124 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15124 NP_068800.2 567 62225 S525 T L R L Y A E S Y E R D P S G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092895 567 62263 S525 T L R L Y A E S Y E R D P S G
Dog Lupus familis XP_533534 494 54693 Y453 I R L Y A E S Y E R D P S G H
Cat Felis silvestris
Mouse Mus musculus Q8BZF8 567 62202 S525 T I R L Y A E S Y E R D P S G
Rat Rattus norvegicus P38652 562 61385 S520 T I R L Y I D S Y E K D A A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516667 611 66492 G565 G W T E G E E G K G E E P G P
Chicken Gallus gallus XP_424802 696 75805 S654 T L R I Y A E S Y E K D P S Q
Frog Xenopus laevis NP_001080172 562 61582 S520 T I R L Y I D S Y E K D L Q K
Zebra Danio Brachydanio rerio NP_001119868 567 62237 E524 A T V R I Y A E S Y E R D P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUY9 560 60748 I518 G A T V R L Y I D S Y E K E N
Honey Bee Apis mellifera XP_395366 563 61940 S521 T I R V Y V D S Y E D D P T S
Nematode Worm Caenorhab. elegans NP_494886 568 61736 I526 R L Y V D S Y I P S N D T S R
Sea Urchin Strong. purpuratus XP_001177674 560 61460 S518 T V R M Y I D S F E S D Q S K
Poplar Tree Populus trichocarpa
Maize Zea mays P93805 583 63023 Q541 T I R V Y I E Q Y E K D S S K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SGC1 585 63463 Q543 T I R L Y I E Q Y E K D A S K
Baker's Yeast Sacchar. cerevisiae P37012 569 63070 K527 T I R L Y I E K Y C D D K S Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.2 84.1 N.A. 97.5 65.6 N.A. 74.1 66.6 65.4 77 N.A. 49.7 51.3 52.6 53.9
Protein Similarity: 100 N.A. 99.4 86.4 N.A. 98.9 83 N.A. 77.9 73.8 82.5 89.5 N.A. 69.3 70.7 69.7 72.4
P-Site Identity: 100 N.A. 100 0 N.A. 93.3 53.3 N.A. 13.3 80 53.3 0 N.A. 0 53.3 20 46.6
P-Site Similarity: 100 N.A. 100 0 N.A. 100 80 N.A. 20 93.3 73.3 0 N.A. 13.3 80 33.3 73.3
Percent
Protein Identity: N.A. 51.1 N.A. 51.4 43.9 N.A.
Protein Similarity: N.A. 67.7 N.A. 68.3 61.6 N.A.
P-Site Identity: N.A. 53.3 N.A. 60 53.3 N.A.
P-Site Similarity: N.A. 73.3 N.A. 73.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 7 25 7 0 0 0 0 0 13 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 25 0 7 0 19 75 7 0 0 % D
% Glu: 0 0 0 7 0 13 50 7 7 63 13 13 0 7 7 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 13 0 0 0 7 0 0 7 0 7 0 0 0 13 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 7 44 0 7 7 38 0 13 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 7 7 0 32 0 13 0 32 % K
% Leu: 0 25 7 44 0 7 0 0 0 0 0 0 7 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 0 7 38 7 7 % P
% Gln: 0 0 0 0 0 0 0 13 0 0 0 0 7 7 13 % Q
% Arg: 7 7 69 7 7 0 0 0 0 7 19 7 0 0 7 % R
% Ser: 0 0 0 0 0 7 7 50 7 13 7 0 13 57 7 % S
% Thr: 69 7 13 0 0 0 0 0 0 0 0 0 7 7 0 % T
% Val: 0 7 7 25 0 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 7 69 7 13 7 63 7 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _